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Our research focuses on the relationship between development and cancer, particularly in the brain. We are interested in how normal stem cells and progenitors make decisions, such as when to divide and when to differentiate. We are also interested in how those decisions go wrong in cancer.
Major areas of investigation are listed below. Please click on the headings to learn more about a particular area.
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The role of fibroblast growth factors, netrins, chemokines and other signals in cerebellar development
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The role of migration, differentiation and survival genes in medulloblastoma
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STEM CELLS AND THE ORIGIN OF BRAIN TUMORS
Identification and characterization of cerebellar stem cells, and the role of stem cells and progenitors in initiation of medulloblastoma
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