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Below are some of the publications from our lab. Click the "open pdf" link to open the publication in a new window.
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| Identification of CD15 as a Marker for Tumor-Propagating Cells in a Mouse Model of Medulloblastoma.
Read TA, Fogarty MP, Markant SL, McLendon RE, Wei Z, Ellison DW, Febbo PG and Wechsler-Reya RJ (2009) Cancer Cell. 15: 135-147. | | open
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| N-myc alters the fate of preneoplastic cells in a mouse model of medulloblastoma.
Kessler JD, Hasegawa H, Brun SN, Emmenegger BA, Yang ZJ, Dutton JW, Wang and Wechsler-Reya RJ (2009) Genes Dev. 23:157-70. | | open
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| Stem cells and the origin and propagation of brain tumors.
Emmenegger, BA and Wechsler-Reya RJ.(2008) J. Child Neurol. 23:1172-78. | | open
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| Medulloblastoma can be initiated by deletion of patched in lineage-restricted progenitors or stem cells.
Yang ZJ, Ellis T, Markant SL, Read TA, Kessler JD, Bourboulas M, Schüller U, Machold R, Fishell G, Rowitch DH, Wainwright BJ, Wechsler-Reya RJ.(2008) Cancer Cell 14:135-45. | | open
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| Fibroblast growth factor blocks Sonic hedgehog signaling in neuronal precursors and tumor cells.
Fogarty, M.P., Emmenegger, B.A., Grasfeder, L.L., Oliver, T.G. and Wechsler-Reya, R.J. (2007) Proc Natl Acad Sci 104:2973-8. | | open
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| Hit ‘em where they live: Targeting the cancer stem cell niche.
Yang, Z.J. and Wechsler-Reya, R.J. (2007) Cancer Cell 11:3-5. | | open
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| The neurobiology of neurooncology.
Read, T.A., Hegedus, B,, Wechsler-Reya, R., Gutmann, D.H. (2006) Ann Neurol. 60:3-11. | | open
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| Isolation of neural stem cells from the postnatal cerebellum.
Lee, A., Kessler, J.D., Read, T.A., Kaiser, C., Corbeil, D., Huttner, W.B., Johnson, J.E. and Wechsler-Reya, R.J. (2005) Nat. Neurosci. 8:723-9 | | open
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| Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma.
Oliver, T.G., Read, T.A., Kessler, J.D., Mehmeti, A., Wells, J.F., Huynh, T.T., Lin, S.M. and Wechsler-Reya, R.J. (2005) Development 132:2425-39. | | open
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| Morphing into cancer: The role of developmental signaling pathways in brain tumor formation.
Fogarty, M.P., Kessler, J.D. and Wechsler-Reya, R.J. (2005) J. Neurobiol. 64:458-475. | | open
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| Getting at the root and stem of brain tumors.
Oliver, T.G. and Wechsler-Reya, R.J. (2004) Neuron 42:885-88.
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| Transcriptional profiling of the hedgehog response: A critical role for N-myc in proliferation of neuronal precursors.
Oliver, T.G., Grasfeder, L.L, Carroll, A.L., Kaiser, C., Gillingham, C.L., Lin, S.M., Wickramasinghe, R., Scott, M.P. and Wechsler-Reya, R.J. (2003) Proc. Natl. Acad. Sci. 100:7331-6. | | open
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| Analysis of gene expression in the normal and malignant cerebellum.
Wechsler-Reya, R. J. (2003) Recent Prog. Horm. Res. 58:227-248 | | open
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| Caught in the matrix: How vitronectin controls neuronal differentiation.
Wechsler-Reya, R. J. (2001) Trends Neurosci. 24:680-2. | | open
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| The developmental biology of brain tumors.
Wechsler-Reya, R. J. and Scott, M.P. (2001) Annu. Rev. Neurosci. 24:385-428.
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| Control of neuronal precursor proliferation in the cerebellum by sonic hedgehog.
Wechsler-Reya, R. J. and Scott, M.P. (1999) Neuron 22:103-114. | | open
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